In two subgroups, individuals with 'purely' acquired CVI and with 'purely' genetic CVI, the ocular variables (such as strabismus, pale optic disc and visual field defects) were compared.
To compare the optic disc and visual field (VF) alterations in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG).
3 Clinical hallmarks of RP include bone spicule deposits, attenuated retinal blood vessels, optic disc pallor, visual field loss, and abnormal, diminished or non-recordable electroretinographic responses.
Moreover, no significant changes in optic disc and visual field defect were noted by investigators, and structural and functional parameters remained stable over 24 months.
Individuals with IOP less than 21 mm of Hg were also included, who had cupping of the optic disc and visual field changes characteristic of POAG.
Inclusion criteria were normal ophthalmic findings, especially normal appearance of the optic disc, normal visual fields and intraocular pressure (IOP), and lack of significant retinal disorder.
The highest level of evidence requires optic disc and visual field abnormalities (VCDR or asymmetry in the 97.5th percentile or more for the normal population with a definite glaucomatous visual field defect).
Three months later a second ophthalmologic exam reported that initial temporal pallor of the optic disc and visual acuity was decreased to 1/20 both eyes with bilateral cecocentral scotoma.
Twenty one patients were diagnosed as having glaucoma (Table 1): the most common condition was primary open angle glaucoma (POAG) in which IOP exceeded 22 mmHg on at least 2 occasions before treatment, there was cupping of the optic disc and visual field defects characteristic of glaucoma were present.
Primary open-angle glaucoma (POAG) is defined as a chronic and progressive disease, characterized by acquired loss of optic fibers, glaucomatous disc progression, visual field changes, and open angles in the absence of known underlying cause.
