Sentence examples for disc compartment from inspiring English sources

Much of what is described is analogous to the roles of transcription factors and localized Notch activation in imaginal disc compartment systems, though much of this parallel is not explored in the text.

doi: 10.7554/eLife.01004 Image Cell death in the Drosophila posterior wing disc compartment (red) induces cell death (blue) in the anterior compartment (green) All animal cells contain the seeds of their own destruction: inactive forms of enzymes called caspases.

The reduced clone survival upon overexpression of mFwe1-HA and mFwe3-HA was not due to a toxic effect of heterologous protein overexpression, because overexpression of mFwe1-HA or mFwe3-HA throughout the whole posterior imaginal disc compartment or in the entire fly did not compromise cell viability (Fig. 2D and data not shown).

We quantified the number of cells in mitosis, detected by the expression of Phospho-Histone3, in the anterior and posterior wing disc compartments, and the size of the corresponding compartments.

Interestingly, induction of clones mutant for thickveins, encoding the Dpp receptor, has been shown to result in cell autonomous expulsion of the clones in both anterior and posterior wing disc compartments [46], [47], [48].

In imaginal discs, compartments of lineage restriction provide one axis of asymmetry along the A/P axis but no evidence for lineage restricted regions has been found in other axes such as the D/V axis of legs or antennae.

We labeled the wing disc A/P compartment border in either of two ways, by expressing a GFP reporter transgene controlled by ptc or by hh.

hui is one of three genes identified by our analysis that is expressed in a stripe along the wing disc A/P compartment boundary.

We next inhibited cell death using UAS-p35 together with a transgene of UAS-Sak and expressed it specifically in the wing disc posterior compartment using the engrailed (en -Gal4 promoten -Gal4

Notch signaling is also required for the wing disc D/V compartment border (Blair et al., 1994; Cohen et al., 1992; Diaz-Benjumea and Cohen, 1993; Irvine and Wieschaus, 1994; Micchelli et al., 1997; Rauskolb et al., 1999), although the mechanism may not be the same.

In Drosophila wing imaginal discs, posterior (P) compartment cells secret Hh protein which acts over a short range on the anterior (A) compartment cells by forming a local concentration gradient [3], [4].