Sentence examples for disc activity from inspiring English sources
This targets caspase-8 for proteasomal degradation and, hence, limits DISC activity.
Recent evidence suggests post-translational modification by ubiquitination to be a crucial regulator of DISC activity.
Conversely, Rosen et al. found increased disc activity in those with degenerative changes [ 20].
Stimulation of TCR/CD3 in human peripheral blood T lymphocytes mediated upregulation of c-FLIPS, which inhibited CD95-dependent apoptosis by blocking DISC activity.
Consequently, TRAIL sensitization by CDK9 inhibition is likely to require changes in intracellular modulators of the TRAIL apoptosis pathway that should enhance DISC activity and possibly additional downstream steps in the pathway.
The CD95 death-inducing signaling complex (DISC) and regulation of CD95 DISC activity by its key inhibitor c-FLIP, have been vigorously investigated by modeling approaches, and therefore will be the major topic here.
The company would no longer advertise its dial-up service on television or mail software discs, activities that brought in hundreds of thousands of new customers a quarter, partly making up for the rapid defection of members to high-speed offerings from cable and phone companies.
The cfu number was calculated per mg fresh weight per seedling or per leaf disc Kinase activity assays were performed on extracts from 14 days old seedlings treated with Salmonella for 0, 15, 30 or 60 min. Cleared cell extracts with equal amounts of proteins were subjected for 2 h immunoprecipitation with 2 µl MPK specific antibodies and 25 µl protein A-Sepharose beads.
Representative actograms of disc running activity in D1R WT (A and C ) and D1R KO (B and D ) mice.
However, in mature third instar discs Notch activity and Wg expression are not maintained in the mutant background (compare Figures 6C and 6E).
10.7554/eLife.03781.008 Figure 3. Disc-running activity of D1R KO (n = 4, red curves and bars) and WT/HT mice (n = 12, blue curves and bars) during ad-lib and temporal food restriction schedules.
