Sentence examples for disassembly rate from inspiring English sources

We demonstrate that spherical shells emerge naturally when the strain relaxation rate (corresponding to internal network reorganization) is slower than the disassembly rate (corresponding to F-actin depolymerization).

Our model predicts that the disassembly rate of MTs strongly influences the MT accumulation rate at chromatin.

The mean FA disassembly rate is significantly higher in p130Cas WT cells (1.9 2.0 fold) than for all other cell types, and the mean FA disassembly rates are not significantly different between the other cells (Fig. 6C).

Secondly, as already proven by mathematical analysis [50], fast reincorporation of dissociated labels into the same photobleached area retards FRAP kinetics substantially slower (∼by half) than the true actin disassembly rate [6], [50].

However, in cells, studies showing a marked reduction in the actin disassembly rate by inactivation of cofilin [12], [22], [23] provide evidence for an essential role of cofilin in actin disassembly.

Given the much slower disassembly rate of the pointed-end side of filaments in lamellipodia (the dissociation rate of Arp2/3 complex, 0.048 s−1 [12]), it is tempting to speculate that cellular actin filaments might undergo one filament-end (barbed-end) dynamicity analogous to microtubules rather than filament treadmilling.

In modeling FA disassembly rates, we noted prominent discontinuous FA disassembly, particularly in the p130Cas signaling deficient cells.

The simulation employed in the above FRAP study [8] does not consider the presence of mixed populations of F-actin with different disassembly rates.

The similar defects observed in all p130Cas mutants implicate SD tyrosine phosphorylation mediated by Src recruitment to the SBD as the key signaling function of p130Cas in stimulating FA assembly and disassembly rates, similar to leading edge protrusion.

Similar to the results for leading edge protrusion, this analysis shows that the SD 15F mutation alone is sufficient to reduce both the FA assembly and disassembly rates to the levels seen in Vector cells.

The marked difference between the CP dissociation and the actin disassembly rates led us to hypothesize that filament severing as well as end-to-end annealing might take place frequently [12].