Combined with the characteristics of the various stages of product life cycle, disassembly criteria for modular design of machine tools for remanufacturing have been established from the aspects of materials selection, remanufacturing process performance, use and maintenance performance, economic efficiency, and functional and physical feasibility.
Both microtubule disassembly and cell cycle arrest induced by DATS were cancelled by the simultaneous treatment of the cancer cells with sulfhydryl reagents such as L-cysteine, glutathione (GSH) or N-acetyl L-cysteine.
These results indicate that with respect to the side chain structures of trisulfide compounds, the two alkenyl groups, but not the alkyl group, play a critical role in both microtubule disassembly and cell cycle arrest.
The existence of such links is not entirely unexpected, as cilia must be dismantled, releasing the centrioles before cells divide (Satir and Christensen, 2007); phosphorylation of the dynein light chain TCTEX1 is pivotal in both ciliary disassembly and cell cycle progression in ciliated cells (Li et al., 2011).
The activity of the SCF complex is regulated by cycles of disassembly and assembly corresponding to cycles in neddylation and deneddylation.
Successful remanufacturing of electric and electronic products must meet the challenges of continuously falling prices for new products, short life cycles, disassembly of unfriendly designs and prohibiting costs in high-wage countries.
Successful remanufacturing of mobile phones must meet the challenges of continuously falling prices for new phone models, short life cycles, disassembly of unfriendly designs and prohibiting transport, labor and machining costs in high-wage countries.
The hallmark activity of CSN consists of the deneddylation of the cullin subunit of cullin-RING E3 ligases (CRLs), which favors CRL disassembly to maintain cycles of CRL assembly and disassembly that are needed protect CRL components from self-destruction (Cope et al. 2002).
In live cells expressing For3p-3GFP from its native promoter, Martin and Chang [4] observed that the association of For3p with the cortical foci is transient: For3p dissociates from the tips of actin cables within seconds, forming dots which passively follow actin cable retrograde flow and disassembly in a turnover cycle similar to actin (Fig. 1A).
3) The authors show that the splicing isoform of Pericentrin (B and S) might underlie centrosome disassembly during cardiomyocyte cell cycle arrest.
Both DATS-induced microtubule disassembly and the cell cycle arrest were cancelled by the simultaneous treatment of the cancer cells with 2 mM L-cysteine, glutathione (GSH) or N-acetyl L-cysteine.
