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Occasionally, the science doesn't quite do what is hoped – a study in Pakistan, for instance, funded by a leading soap manufacturer disappointingly found that antibacterial soap was really no more effective at cleaning hands than normal soap.
A subsequent report that focused on infants who received their first shot at 6 to 12 weeks old disappointingly found that the impact on clinical malaria dropped sharply to only a 31% reduction in cases.
However, while I wandered the halls, I disappointingly found that certain rooms – like the lecture theatres and some smaller classrooms – were protected with the same student swipe terminals that had stumped me earlier that morning.
Selenium was proposed as a promising chemopreventive agent [ 5, 6], possibly through its role as an antioxidant and cofactor of enzymes such as glutathione peroxidase, but SELECT disappointingly found a non-statistically significant increase in prostate cancer incidence with selenium supplementation [ 7].
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"Disappointingly, we found no difference in the number of new infections between these two randomised sets of clusters," says Deenan Pillay, director of the Africa Centre and professor of virology at University College London.
Disappointingly, we found no overlap with the proteins identified in the current study versus those in the previous publication [18].
More disappointingly, we found suggestion of a lack of co-operation at an organisational level resulting in, for example, evidence of insufficient information being transferred between hospital staff who considered that once they had discharged a patient they had no further responsibility to provide information to a patient's GP about the patient's anti-coagulation status.
Disappointingly, she finds that most of the negative comments come from women.
But the actual meat of the film itself – its story and ideas – I found disappointingly vacuous.
American Trilogy, so impressive in landing the County Hurdle, found disappointingly little under pressure and came third.
We recently found disappointingly poor PCR sensitivity using a three color real-time PCR assay that was capable of detecting S. Typhi, S. Paratyphi A and an incorporated internal control [ 49].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com