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Disappointing updates from Intel and IBM did not help sentiment.
Elsewhere Barclays is down 3.05p to 225.9p following disappointing updates from Deutsche Bank and UBS.
The day's rise came despite some disappointing updates, and was helped by a strong mining sector.
A number of disappointing updates from major companies also soured the mood.
Mining shares are supporting the UK market despite a series of disappointing updates elsewhere putting pressure on shares.
But luxury goods group Burberry is down 25p at £12.49 after disappointing updates from rivals Hermes and Richemont.
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Overall another disappointing update and we remain cautious.
And that despite a 10% fall in constituent member Apple after its disappointing update.
In a rising market technology group Smiths is on the slide after a disappointing update.
Rolls-Royce was still under pressure following last week's disappointing update, down 19p to £10.06.
Standard Chartered is leading the fallers, down 25.2p to 648.1 after Tuesday's disappointing update.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com