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The chief investigators on the study, Dr. James O. Kahn at the University of California at San Francisco and Dr. Stephen W. Lagakos at the Harvard School of Public Health, then prepared a paper on the disappointing study.
All in all, this apparently disappointing study highlights the need to clarify the interest and limits of plasma citrulline concentration in the critically ill.
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Fiber has also been knocked around a bit lately, after three disappointing studies failed to find that a high-fiber diet helped to prevent colon cancer.
Not surprisingly, the delivered dose in this study was only about half of that in awake, cooperative infants. 2 Based on these disappointing studies, a recent Canadian guideline discourages parents from attempting to deliver aerosols to their infants during sleep.
Although the interim outcomes published last fall were disappointing, the study is still ongoing, with full results expected in 2014.
The political scientist Richard Locke, looking back on his long and disappointing experience studying the voluntary labor standards adopted by Nike, also cites the I.L.O.
Although prior treatments directed at intervertebral disks have been disappointing, recent studies show promising improvement of pain and function after a single intradiskal injection of methylene blue.
In addition, conflicting published results and disappointing clinical studies have made single cancer biomarkers highly controversial (Shah et al, 2009).
Technical advances, particularly in MRI and CT, have resulted in a significant improvement in image quality and although early studies reported disappointing sensitivities, recent studies have reported improved detection [ 3].
First, the response rates of the O&G and D&V doctors were somehow disappointing in this study and better collaboration with relevant professional associations is required for future studies of the type.
While the efficacy of gefitinib in monotherapy studies in advanced disease was disappointing, neoadjuvant presurgical studies with both gefitinib and erlotinib demonstrated clear biological effects with the drugs in oestrogen receptor-positive breast cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com