These are equivalent to CR (disappearance), PR (reduction of ≥30%), SD (reduction <30% or enlargement ≤20%), or PD (enlargement ≥20%) in unidimensional RECIST criteria, respectively (reviewed in [ 27]).
Previous studies have suggested high mutations in BCP and preC regions are major cause for the loss of HBeAg but without true disappearance or reduction of viral load.
Local application of magnesium sulfate into the lesion and peroral administration of magnesium lactate resulted in disappearance or reduction in size of the lesions [ 60].
Observation of TCho before treatment and its disappearance (or reduction) after treatment may be a useful indicator of response of locally advanced breast cancer to neoadjuvant chemotherapy.
In observation under EM, typical apoptotic characteristics were found, including cell membrane blebbing, microvillus disappearance or reduction, and separated apoptotic bodies.
Gene suppression by RNAseH, silencing, or translational blockade can be more problematic to assess because the disappearance or reduction in abundance of a transcript or protein is measured in a negative assay.
Although having their viral DNA load detected (> 103 copies/ml), some patients in our study were shown to be HBeAg negative, suggesting their HBeAg negativity was not caused by the disappearance or reduction of viral replication.
Primary endpoints: 1) disappearance or reduction of symptoms during Ni-rich food re-introduction (patients reported their clinical status in a diary and made a VAS at each control visit), and use of rescue medications (reported in the diary); 2) tolerability evaluated on the basis of side effects (reported in the diary).
On the basis of these observations, we designed the present trial to study the clinical efficacy and tolerability of NiOHT in SNAS, evaluating the disappearance or reduction of systemic symptoms during the re-introduction of Ni-rich foods, the use of rescue medications and the appearance of side effects.
These spectra revealed either a reduction, disappearance or broadening of the peaks after the process of impregnation.
In contrast, with undifferentiated carcinomas there was only an ill-defined area with disappearance or a reduction in the density of capillaries in the noncancerous mucosa.
