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These disadvantages have to be traded against reliability.
However, possible advantages and disadvantages have to be discussed with the patient in detail.
Do not provide actual information (like data collected in a survey, case history) in the Research Design except in the Introduction and Methodology, where definitions, advantages and disadvantages have to be provided.
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Longitudinal studies also have some disadvantages that have to be taken into account (for a more detailed description see Wunsch et al. 2010, pp. 9 12).
Moreover, depending on the intended application, the two approaches might have both advantages and disadvantages and have to be weighed very carefully.
ICU treatment of surgical patients comes along with major disadvantages that have to be justified by an acceptable short-term and long-term outcome.
It should be remembered that several percutaneous techniques, intrusive and extrusive, are now commercially available and each of them has advantages and disadvantages that have to be addressed individually when a specific tracheostomy technique is chosen for the individual patient.
Reducing the complex functions of the in vivo state to in vitro settings bears both benefits and disadvantages which have to be taken into account when interpreting our findings.
However, the use of ceftriaxone in low-resource countries has considerable disadvantages which have to be considered: (i) the drug has to be adminstered intravenously or intramuscularly; (ii) well trained staff is necessary; (iii) uncritical use may promote the development of resistance; (iv) ceftriaxone is approximately 3 to 10 times more expensive than amoxicillin.
Keep in mind that the disadvantage would have to be very large (up to twofold) to overcome the fact that all asexual individuals are female and can give birth.
Each technique has advantages and disadvantages and they have to be considered together.
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