Exact(1)
Development of mOGCT may involve the combined effect of genetic alterations or predisposition and disadvantageous environmental factors such as exposure to maternal hormones, external endocrine disruptors, or adverse lifestyle-related factors that disturb the cells' normal biochemistry.
Similar(59)
However, Paenke et al. (2007) found that nongenetic inheritance is disadvantageous when environmental fluctuations are very rapid and unpredictable from current environmental cues.
Additionally, the advantages of controllability and affordability of diesel generator sets are contrasted to their disadvantageous performance at partial load and environmental harmfulness.
Thus, an allelic variant may be associated with lowered ability only when it co-occurs with disadvantageous alleles on other genes or with specific environmental circumstances; against a different background, it may be neutral, or even advantageous.
Additionally, designers and engineers of farming systems neglect the animals' potential in the design of husbandry systems, resulting in disadvantageous trade-offs between animal welfare and economic and environmental sustainability aspects.
The rapid global increase in the number of individuals with type 2 diabetes (T2D) was considered caused by increasing life expectancy, sedentary lifestyle and disadvantageous diet habits, possibly in combination with genetic and environmental factors [ 1, 2].
Consequently, while a larger Ne is more advantageous than a smaller Ne in the wild (larger Ne populations will on average be more capable of responding to environmental change than smaller Ne populations), it might be disadvantageous in captivity (larger Ne populations may become more adapted than smaller Ne populations to the captive environment).
In any case, more severe environmental change (larger distance or rate at which the optimum moves) is disadvantageous to rescue in these models (Lynch and Lande 1993; Bürger and Lynch 1995; Gomulkiewicz and Holt 1995; Gomulkiewicz and Houle 2009; Kopp and Matuszewski 2014).
If outsourced production happens on terms that are highly disadvantageous for the outsourcing suppliers, it creates conditions for a race to the bottom on environmental and working conditions, as suppliers attempt to recover margins wherever they can.
It would be very disadvantageous for innovation.
He moves in a disadvantageous direction.
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