The correlation measure of the entire data is beneficial for determining the strength of association between nodes (see Section 2.4) but disadvantageous for detecting the direction of interaction.
In fact, there is a correlation between Mecp2 "dosage" and phenotype severity, indicating a narrow normal expression range, with deviance in both directions being disadvantageous (Chao & Zoghbi, 2012).
For instance, the MS predicts that genetic mutations (and hence novel phenotypes) will be random in direction and typically disadvantageous, whereas the EES predicts that novel phenotypic variants will frequently be directional and functional.
In the standard account, genetic mutations (and novel phenotypes) are random with respect to direction, rate and location, typically disadvantageous, and appear in a single individual.
Although this CFA pattern is disadvantageous with respect to the spatial resolution along the horizontal direction, we focus on the improvement of sensitivity and color fidelity by resolving the rapid saturation problem.
Bird's interrupter had the medically disadvantageous feature that current was supplied in opposite directions during the make and break operations.
261 Periodic structures are both angle-dependent and wavelength-dependent and this is generally disadvantageous for PV cells due to the broad solar spectrum and the time-varying illumination directions.
It would be very disadvantageous for innovation.
Cardiac glycosides, however, have disadvantageous side effects.
