Sentence examples for disadvantageous alterations from inspiring English sources

We have neglected disadvantageous alterations since in large tumors, cells carrying such alterations are likely unable to establish a surviving clone, but go extinct due to their deleterious characteristics.

Aging is the key nonmodifiable cardiovascular risk factor and leads unequivocally to diverse disadvantageous alterations of the cardiovascular system with the consequence of increased cardiovascular morbidity and mortality [ 1].

In turn, impaired restoration (reestablishment) of the totipotency/pluripotency of embryonic cell lines in the first phase of epigenetic reprogramming (i.e., gene dedifferentiation) during preimplantation development by the blastocyst stage may trigger disadvantageous alterations in the second phase of donor nuclear reprogramming.

On the contrary to adults, they often cannot make any alterations to disadvantageous environment.

Development of mOGCT may involve the combined effect of genetic alterations or predisposition and disadvantageous environmental factors such as exposure to maternal hormones, external endocrine disruptors, or adverse lifestyle-related factors that disturb the cells' normal biochemistry.

Although the LPS challenge is a simplified inflammation model, the present results suggest that such alterations in cytokine release can be disadvantageous for recovery from frequently occurring bacterial infections of the gastrointestinal and respiratory system in pigs.

"Everyone can together decide on a new short term disadvantageous but long term highly advantageous change".

These deficits could be caused by alterations in the ability to incorporate feedback (patients fail to learn after losing money using disadvantageous dice) or by impairment in executive functions (patients fail to elaborate the right decisions correctly).

It would be very disadvantageous for innovation.

He moves in a disadvantageous direction.

Cardiac glycosides, however, have disadvantageous side effects.