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Another effective antiresorptive drug is Evista (raloxifene), which has an added advantage of reducing the risk of breast cancer, but the disadvantage of increasing the risk of deep vein blood clots and hot flashes.
That course would have the advantage of restoring legitimacy to the rather shaky institutions set up by the Good Friday Agreement of three years ago, and the disadvantage of increasing the power of Mr Adams and the fire-and-brimstone unionist, the Reverend Ian Paisley, at the expense of their more moderate counterparts, the nationalist John Hume and Mr Trimble.
A big aggregate has the disadvantage of increasing competition between individuals in the groups [73], [25].
The same gene variants which result in rapid activation of a vigorous inflammatory response to infection may have the disadvantage of increasing the risk of auto-immune and inflammatory diseases later in life [8], [9].
The multiple R2 represents the coefficient of determination and has the disadvantage of increasing with the amount of predictors added.
As a result of point (ii) it is possible to compare the selective advantage of adding new amino acids and the disadvantage of increasing translational error.
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In our example, the programmed advantage of increased theoretical discriminability for the sequential condition is more than counteracted by the programmed disadvantage of increased criterion variability and leads to a lower empirical ROC.
In comparison to linear design, adaptive or predictive control systems can offer improved performance, albeit with the disadvantage of increased complexity, which can be prohibitive in the context of RM.
However, there is also the disadvantage of increased complexity, and increased housekeeping at each iteration.
Using a voxel size of 0.125 mm has the potential to yield in vivo volume measurement of teeth comparable to micro-CT in vitro analysis [20], but understandably has the disadvantage of increased patient radiation dose.
In regard to this it should be noted that the potential disadvantage of increased mutation frequency in activated T cells undergoing very rapid division is counterbalanced by the fact that the vast majority of these effector CD8+ T cells will undergo apoptosis during the contraction phase of the immune response.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com