The improved diagnostics and, thereby, the reduction of overtreatment will benefit the individual patient more than the disadvantage of delaying treatment.
Women whose CIN3 has already regressed before their first smear and does not recur may suffer an increased risk of invasive cancer for the rest of their lives, and this long-term risk could be an important disadvantage of delaying the age at which routine screening begins (Peto et al, 2004).
This model has the disadvantage of delays in the management of unexpected intrapartum complications in otherwise low-risk pregnancies, therefore, there is a need to re-evaluate the models of birth care in South Africa.
Disadvantages of the MOW include the possible need for bone graft and the risk of delayed or non union.
COX inhibitors are the most common pain relievers in these cases but they have the disadvantage of inhibiting and delaying bone strength and bone repair.
General Idris accused the West of delaying with endless meetings, summits and requests for new "guarantees" that extremists would not get arms, and said this left the rebels at a huge disadvantage against Mr. Assad's forces.
The fundamental disadvantages of the delay line were that random access is impossible and, moreover, the time taken for an instruction, or number, to emerge from a delay line depends on where in the line it happens to be.
This QTL region is probably the result of the presence of a major gene for flowering, in which the crop allele confers a selective disadvantage by delaying bolting (Hartman et al. 2012).
However, the disadvantage of the intragastric approach includes delayed gastric emptying and predisposes to inadequate nutrient administration.
However, cord blood has the disadvantage of limited HSC content and shows delayed hematological reconstitution.
