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The main disadvantage of applying PCA is the loss of information, since there is no guarantee that the sacrificed information is not relevant to the aims of further studies, and also there is no guarantee that the largest PCs obtained will contain good features for further analysis [21, 57].
The disadvantage of applying whole-genome CNV analysis is the limitation in detection of smaller sized CNVs.
Though configurable for either Safe-Harbor or Limited Data Sets, the disadvantage of applying De-ID© is the removal of a small amount of clinical information during the de-identification process.
On the other hand, apart from limitations involving duplication and deletion events [ 32- 34], one disadvantage of applying sequence-based markers alone stems from the inability to distinguish whether different gene copies represent true homoeologs representing whole chromosome sets or mere chromosome segments acquired through hybridization or introgression.
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The approach described in the paper overcomes the disadvantages of applying crude enzyme on zymogram and combines effective isolation with identification assay.
In this article from the USA, Charles G. Stolberg, Executive Director of the Submersible Wastewater Pump Association, describes some of the contributing components of the variable speed pumping system and how they interact with certain other components, and provides information to properly evaluate the advantages and disadvantages of applying such a design to submersible pumping equipment.
A summary of our findings is presented with a discussion of both the advantages and disadvantages of applied simulation to training.
The disadvantages and limitations of applying this method did not fit the objective of our study.
Dyson claims the disadvantage was driven home by discrepancies in the bureaucratic process of applying for patents.
Some of the disadvantages of biofuels apply mainly to low-diversity biofuel sources corn, soybeans, sugarcane, oil palms which are traditional agricultural crops.
The advantages and disadvantages of the applied methods and models are presented and discussed.
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