Sentence examples for disable resistance from inspiring English sources

For example, compounds which disable resistance mechanisms, such as inhibitors of drug-degrading enzymes or of efflux pumps can neutralize the advantage of resistance [2], [3].

It follows that the general susceptibility of Irgm1-deficient mice to protozoal infection may be accounted for as a regulatory failure that disables the IRG-dependent resistance mechanism.

Whole-body deletion of Irs2 causes insulin resistance by disabling insulin signaling pathways; Irs2-deficiency causes hyperphagia and obesity due to impaired insulin signaling in specific populations of hypothalamic neurons (Kubota et al. 2004; Choudhury et al. 2005).

Watched by a few residents, the Iraqis faced no initial resistance, finding and disabling a few roadside bombs as they progressed.

Although mechanisms have yet to be clarified, chronic up-regulation of these mitogenic pathways may selectively disable VDR signaling, leading to 1,25D resistance.

Classical inhibitors of DHFR use an active transport mechanism to gain access to the cell; disabling this mechanism creates a pathway for resistance.

Intrinsic apoptosis resistance of cancer cells often involves disabling of the intrinsic apoptotic machinery.

The clinical trial of the same compound in a medulloblastoma patient led to rapid tumor shrinkage, but was complicated by drug resistance due to a SMO mutation, disabling the binding of GDC-0449 to SMO.

But it is unlikely, at least for now, to alter their resistance to a military strike intended to disable Iran's uranium enrichment facilities.

" Resistance's goal is not to wound or disable.

Sidney Altman and his colleagues at Yale University used one of the bacteria's own enzymes, called RNase P, to disable RNA made from genes that had been linked to drug resistance.