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CMA sensitivity in group V patients whose clinical indications represent "others" (e.g., seizure disorders, learning disability, failure to thrive, etc).
This previously unidentified phenotype comprises postnatal microcephaly, progressive cerebellar atrophy, intellectual disability, failure to thrive, polyneuropathy, hearing impairment, and organ fibrosis with exocrine pancreas insufficiency.
For example, in the case of patients with a learning disability failure to provide adequate information could result in not enough time being allocated to facilitate EEG recording for a person who may have some difficulty co-operating with the investigation.
The LIFE Study is a landmark Phase III randomized controlled clinical trial that will provide definitive evidence regarding the effect of exercise on major mobility disability – failure to complete a self-paced 400 m walk in ≤15 minutes – in older adults, aged 70 89 years who have compromised physical function.
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He seems to have the exterior perfection that Marie and Walter wish for, and yet he feels some kind of interior disability, a failure of something within him.
These include: death, neurological disability, organ failure and organ puncture[ 37].
Biofortification has the potential to help alleviate the suffering, death, disability, and failure to achieve full human potential that results from micronutrient undernutrition-related diseases.
Non-adherence to treatment suggested by health care providers may have serious consequences such as exacerbation of symptoms, development or progression of disability, and failure to attain expected positive treatment outcome [ 22].
PKU can result in several problems in untreated patients, including intellectual disability, liver failure, and reduction of life expectancy [ 1, 2], and its nutritional therapy is accomplished by rigorous diets based on Phe-free protein substitutes, either mixtures of free amino acids or protein hydrolysates [ 3].
The stability of symptoms over the 180-day follow-up is most likely explained by the chronicity of the fibrotic changes with a median (IQR) duration time between last lumbar surgery and inclusion of 2.3 (1.6 3.6) years and by the severity of the condition, with high levels of disability and failure of previous treatments.
A combination of "tick-box" approaches to achieving disability equality, failures by some universities to implement legally required measures, and failures by the Student Loads Company are all hindering disabled students, Education Guardian has learned.
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