Exact(16)
While this assay does not directly screen for activity towards β-amino acids, α-methylbenzylamine constitutes a good model substrate for ω-TAs which also possess activity towards short-chain aliphatic β-amino acids.
By simply modifying the design of the probe DNA molecules, this technique can be used to directly screen other viral DNAs in various human biological samples at the single-molecule level without target amplification.
For example, Ying Cai was involved in the establishment of method to directly screen the producing strain of nisin; Haiqing Hu cloned the complete gene cluster of nisin; Jing Yuan constructed nisin mutants with broader antimicrobial spectra (Yuan et al., 2004), and so on.
This unique one-step real-time differential scanning calorimetry (DSC FTIR microspectroscopic approach has been successfully applied to simultaneously and directly screen and detect pharmaceutical co-crystal formation in systems such as indomethacin saccharin, indomethacin nicotinamide, carbamazepine glutaric-acid, metaxalone–sucarbamazepine glutaric-acidaccharin.
As described above, the predicted biosensors can be used in combinatorial metabolic engineering experiments to directly screen for strains that over-produce 25 out of a total of 50 metabolites producible by E. coli under glucose minimal medium.
In addition to FBDD, NMR can also be used to directly screen larger compound libraries.
Similar(44)
The confusion stems from federal procedures that prevent the agency from directly screening passengers in advance because of privacy concerns when airlines provide passenger information to the government.
The microfluidic origami device was fabricated by directly screen-printed electrodes on wax-patterned cellulose paper in bulk.
Firstly, the origami device was fabricated by directly screen-printing electrodes on wax-patterned pure cellulose paper.
By reverse genetics, putative mutants carrying the candidate allele can be directly screened for the target phenotypic changes.
Based on our study, we suggest an alternative approach of directly screening all ARDS patients with BCCE, which we believe can be done quickly at the bedside.
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