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A recent development directly introduces light sensitivity into proteins by utilizing photosensitive unnatural amino acids (UAAs) incorporated using the genetic code expansion technique.
To prevail over this obstacle of drug-induced systemic toxicity, a novel approach termed "ATTEMPTS" (antibody targeted triggered electrically modified prodrug type strategy) was designed, which directly introduces both of the targeting and prodrug features onto the protein drugs.
In this paper, a modification of the CCM is proposed that directly introduces the effect of depth and the shape of the tunnel cross-section in the determination of the radial displacement of the tunnel.
This amination provides the first example of CN bond formation which directly introduces acyclic and cyclic amines to the α-position of phosphonates in one step.
By contrast, shotgun lipidomics directly introduces lipids that were ionized by the soft electrospray ionization (ESI), the matrix assisted laser desorption/ionization (MALDI), or desorption electrospray ionization (DESI), and detects the lipids by MS, with separation of lipids achieved solely on the basis of mass-to-charge ratio.
First, we examined by immunofluorescence the sub-cellular distribution of endogenous RECQ1 in human cells either untreated or exposed to IR which directly introduces DNA strand breaks.
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Assumed bending behavior is directly introduced in the higher-order strain term.
This model can be directly introduced in codes based on the Distinct Element Method.
The Hamilton principle is directly introduced in a suitable finite element software to solve the problem.
Our strategy involved directly introducing tadalafil as guest molecule into microporous silica as host material by incipient wetness impregnation method.
In any of these policy scenarios, new money will be directly introduced into the real economy, stimulating aggregate demand and boosting employment, investment and spending.
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