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All of these pins directly fuse with the corresponding pins on the T6963C.
The method of non-local means (NLM), introduced in [15], may be the first method to directly fuse non-local patches from within the observed image based on vector distances for the purpose of image denoising.
However, our data suggest that HIV-infected cells may also directly fuse with and kill pDCs, which could account for much of the depletion observed in infected individuals.It has been demonstrated that HIV-mediated activation of pDCs involves endocytosis and not membrane fusion [22], so it is possible that HIV kills pDCs by a mechanism independent of that which induces their activation.
The IL-1β-containing autophagosome may directly fuse with the plasma membrane or further fuse with a MVB followed by fusion with the plasma membrane.
Moreover, there is no evidence of amphisome in yeast in which the autophagosomes can only directly fuse with the vacuole, the lysosome counterpart.
For instance, before fusing with lysosomes and forming autolysosomes, autophagosomes can also directly fuse with early and/or late endosomes, to form hybrid structures named amphisomes [ 9, 75] (Fig. 4).
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We hypothesize that when directly fused to Venus-ANAPC4 in context of the large APC/C assembly, the mAID degron is not accessible for recognition by the SCFTIR complex.
From our experimental results, we show that large amounts of sensory-motor information, including raw RGB images, sound spectrums, and joint angles, are directly fused to generate higher-level multimodal representations.
This inferior palpebral muscle is so directly fused with the sheaths of the ocular muscles that it provides cooperative action, opening of the lid on downward gaze being mediated, in effect, mainly by the inferior rectus.
Third, recruiting SCFTIR1 by the mAID-nanobody might be advantageous for degradation of subunits in large protein complexes such as the APC/C, where a directly fused AID degron might not be accessible to the SCFTIR1 complex (Fig. 5 and Supplementary Figure 5).
Previous studies in our laboratory have shown that when the N-terminus of interferon-α2b (IFN-α2b) was directly fused of to the C-terminus of human serum albumin (HSA), the resultant fusion protein (HSA-IFN-α2b) was heterogeneous (migrated as doublets on non-reducing SDS PAGE) and unstable (prone to form covalent aggregates).
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