Sentence examples for directly essential for from inspiring English sources
Furthermore, although W187 is directly essential for Ud/72 NS1 to bind host CPSF30 (thereby contributing to efficient inhibition of cellular pre-mRNA post-transcriptional processing [33]), PR8 NS1 inherently lacks this function [2].
DMAPP is essential for the synthesis of GGPP further downstream, while GGPP is directly essential for the synthesis of casbene.
A previous domain analysis of α-SNAP suggested that a hydrophobic loop within α-SNAP, although not directly essential for NSF activation, could function as a membrane attachment site to promote its recruitment to the SNARE complex (Barnard et al., 1997; Winter et al., 2009).
These phosphorylation events may directly recruit proteins essential for checkpoint activation to damage sites.
Ccr competes with Ter for crotonyl-CoA directly, but Ccr is essential for growth of M. extorquens in both C1 and C2 substrates [ 41].
These data clearly suggest that the chaperone function is directly related and possibly essential for the antiapoptotic function of αA-crystallin.
This transposon family a) has the epigenetic signatures of enhancers, insulators, and repressors, b) directly binds transcription factors essential for pregnancy, and c) coordinately regulates gene expression in response to progesterone and cAMP [ 46].
However, this observation led us to explore the possibility that the presence of FBM sequence in GPCRs might be a conserved feature essential for directly engaging filamin in cells and activating FLNa phosphorylation.
No specific single or complex phospho-epitope on tau is identified as essential for, or directly related to the neurodegeneration.
BAFFR signals primarily through the alternative NF-κB pathway and interacts directly with TRAF3 (this is essential for its signal transduction).
Finally, it is also possible that the neurophysiological measures as performed with TMS do not directly reflect changes in excitability essential for motor learning in this context.
