We directly enumerate the relative frequency (p_{i,j}) that individual i appears in position j across the 13 motifs, which gives the motif position ratio profile (p_{i}=(p_{i,1},ldots2},p_{i,30}{i,30})) for individual i.
This combined approach indeed makes it possible to directly enumerate P65-specific CD4 T cells in the blood during early time points of M. tuberculosis infection, circumventing the ambiguous measurement of antigen-specific T cells in acute infection.
Therefore, we used micro-costing, which directly enumerates and subsequently values each input consumed for each particular participant.
They do not directly enumerate all pathways linking a source set to a target set of compounds.
This allows to reduce the set to be handled and an algorithm to directly enumerate the classes was given by Braga et al. (2008).
In contrast to qPCR and branched DNA assays, the nCounter Analysis System directly enumerates specific RNA molecules by dual probe hybridization, requiring amplification of neither RNA nor signal.
Our experience with requestors indicates that many of them are not interested in utilizing complex terminology structures and prefer directly enumerating concepts of interests for a given scenario step.
Solving this balancing condition for all biochemical reactions in the network, the so called stochiometric matrix, directly enumerates all possible stable pathways of the system allowing equilibrium for their respective internal metabolites.
One notices that extreme pathways and elementary modes while representing pathways (to each flux verifying Sv = 0 correspond a stoichiometrically balanced pathway) do not directly enumerate all pathways linking a source set to a target set of compounds.
Aside from using extreme pathways and elementary modes, we also present in this paper a topological model which directly enumerates all the possible heterologous pathways linking target compounds to a source set of compounds.
