An alternative, but not mutually exclusive, hypothesis is that the enhanced cytokine response directly enhances epithelial cell proliferation and itself predisposes to cancer, in addition to the effects on acid secretion.
Several methods of enhancing collagen II expression have been reported and the main transcription factor recognised for this purpose is Sox9 as it directly enhances collagen II expression by transcriptionally activating the enhancer region of the col2a1 gene in both differentiating MSCs and chondrocytes [ 6].
It also highlights the significant enhancements in the response time introduced by DBAS, which directly enhances the user experience.
Having these media around directly enhances the ecosystem.
This finding indicates that Mnb-mediated phosphorylation of Synj directly enhances Synj activity.
It directly enhances symbiont photosynthesis, and indirectly host metabolism, since symbionts translocate most of their photosynthates to the animal host.
Finally, note that for the nonnested strategy, the value of both options directly enhances the value of the underlying assets associated with the initial product introduction.
To determine whether EPA directly enhances Treg induction, we induced Tregs in the presence of CD3 antibody, CD28 antibody, IL-2 and TGF-β (Fig. 5E).
We also find that supplier quality integration directly enhances competitive performance, and internal quality integration enhances competitive performance both directly and indirectly through supplier quality integration.
More precisely, TRα1 directly enhances the transcription of several components of this pathway, allowing increased expression of β-catenin/Tcf4 target genes and stimulation of cell proliferation.
Second, a large class of natural behaviours is associated with positive affective experience, and thus their performance directly enhances animal welfare.
