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62 Thus, it is highly conceivable that IL-27-induced PD-L1 expression in T cells and tumors could contribute to the protumor effects of IL-27, whose possibility remains to be directly clarified.
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It is one of the general principles of data processing laid down in Article 5 of the Regulation and is applicable to all processing situations.bb Although it does not directly clarify the conditions of consent, the concept of 'purpose limitation' in Article 5 and the concept of 'purpose specificity' in relation to 9(2)(a) are tightly linked (Article 29 Data Protection Working Party 2013, pp 13 14).
This review is from Roy Parker and I would be happy to directly clarify the comments for the authors if desired.
The reviewed studies do not directly clarify whether the nature of stress experienced in vulnerable groups is personal or contextual.
Unfortunately, this study did not directly clarify the relationship between AKI diagnosis and creatinine increase and between fluid overload and urine output decrease.
22 Identification and kinetics of the excited states using time-resolved spectroscopy: For directly clarifying the dynamics of the photophysical processes of 1 a and the chemical reactions of its reactive excited states and intermediates, ultrafast time-resolved UV-visible absorption (TR-UV/Vis), emission (TR-EM), and IR (TR-IR) spectroscopy was employed.
The VIIISelect adsorbent was used as the initial capture column to purify a FVIII compound directly from clarified cell culture fluid prior to further downstream purification.
The C-terminal fusion of this short C-tag to P. falciparum reticulocyte-binding protein homolog 5 achieved >85% recovery and >70% purity in a single step purification directly from clarified, concentrated Schneider 2 cell supernatant under mild conditions.
Currently our methods label DG axon membranes, not synapses directly (we clarified this in the revised manuscript).
Recently, Segura et al. [ 7] described an approach involving heparin affinity chromatography to concentrate LV vector particles directly from clarified supernatants.
Moreover, the ability to capture mAbs directly from clarified harvest without any pretreatment and very high selectivity leading to removal of most host cell proteins are two distinct advantages of protein-A chromatography.
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