This can be associated with symptoms and may require procedures that directly burdens the individual patient [21, 22].
Europe has avoided directly burdening energy-intensive industries such as steel, aluminum and cement companies, "but by doing so cap-and-trade loses much of its environmental benefits," she adds.
Furthermore, chemotherapy directly influences tumor burden, and tumor burden strongly correlates with the incidence of pulmonary metastasis (i.e., metastasis occurs more frequently with larger tumors).
During lowstands of sea level, rivers may dump their sedimentary burden directly on them.
Seeking to shore up its finances in advance, Quebec added a health tax to its 2010 budget, requiring individuals to share a burden directly that was previously paid out of general public revenues or withheld from wages.
There are any number of accounting strategies firms can use to reduce their tax obligations, from moving assets overseas to structuring their business in a way that passes the tax burden directly on to investors.
Dementia is best correlated to synaptic and neuronal loss, rather than directly to pathological burden, and so much interest has been focused on understanding the pathways that lead firstly to the formation of pathology, and then from pathology to synaptic damage, loss and then neuronal death.
PFS, a biological indicator, can be applied to measure tumour burden directly.
In addition, environmental change can affect disease burden directly without necessarily influencing transmission.
These shreps can be computed directly – avoiding the burden of exhaustive enumeration of individual structures.
