Sentence examples for directly bound with from inspiring English sources

As shown in Figure 4b, Kras directly bound with the PI3K p110 α subunit in A549 cells, and transfection with PIK3CA E545K plasmid or PTEN shRNA enhanced such interaction corresponded with increased kinetics of the PI3K/AKT pathway.

Activated FUNDC1 directly binds with LC3 or ATG8 to induce subsequent mitophagy.

FUNDC1 contains a classical LC3-interacting region (LIR) which makes it possible to directly bind with LC3 or ATG8 to induce subsequent mitophagy (Liu et al., 2012).

Then, activated TNIK directly binds with both TCF4 and β-catenin and phosphorylates TCF4.

> To screen specific epitopes that directly bind with the pr protein, ELISA was performed with anti-prM pAb.

Indeed, mtHsp70 was shown to directly bind with Hsp60, and Hsp60 mtHsp70 complex participates in the translocation and folding/assembly of nuclear-encoded proteins in the mitochondrial matrix.

Palacios et al. demonstrated that estrogen directly binds with ER α, a membrane receptor expressed on osteoclast precursors, and decreases the formation of TRAP-expressing osteoclasts [ 27].

The galactose helps in reduction of proteinuria as it directly binds with PF and prevents interaction of PF to galactose residues of podocyte glycocalyx.

Some of the new compounds were also found to inhibit HCV NS3 helicase function in vitro, and one directly bound NS3 with a dissociation constant of 570 ± 270 nM.

GSEA comparison of directly bound targets with the NKX2.2 knockdown/rescue microarray dataset revealed a statistically significant enrichment of NKX2.2 bound targets with NKX2.2 repressed genes (NES = −1.4; p<0.001; Figure 5F).

When PBMC ΤΝFα responses against anti-CII IC were compared with directly coated IgG, there was a left shift in the slope of ΤΝFα response against anti-CII IC, implying that the responder cells needed lower amounts of anti-CII in the form of surface-bound IC than directly bound IgG to respond with comparable TNF production.