The model also reproduced our finding that each spike/s of simple-spike firing rate is associated with an increase of ∼0.005 in the probability of a CS response to an off-direction instruction (data not shown).
The EDS line scan performed in the middle along the longitudinal axis of a single Co85Ni15/Co54Ni46 segmented nanowire (Figure 4a,b) and also across the transversal direction (data not shown) discloses that the Co and Ni content distributions are very uniform in each segment of the nanowire.
Time-lapse movies showed that, like T cells, nocodazole-treated HUVECs frequently changed direction (data not shown), accounting for the lower cell displacement.
Finally, we ran 2D simulations of the yeast model (h = 4) which exhibited good tracking to changes in the gradient direction (data not shown) again resembling the generic FF model with diffusion.
For the restricted analyses (complete cases), results were in the same direction (data not shown).
Three promoters showed activity in only one direction and the remainder exhibited no activity in either direction (data not shown).
For 3994 599 %) of these genes we could confirm changed expression levels in the same direction (data not shown).
There were no significant effects on PEF measured at the same time, although the trend was in the same direction (data not shown).
In comparison, samples produced with a perpendicular orientation displayed a higher degree of disorder and a tendency for rod alignment parallel to the withdrawing direction (data not shown).
