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For THP-1 cells, qRT-PCR compared to microarray results was directionally concordant for all 20 genes.
Analysis of three independent published lung cancer arrayCGH datasets confirmed that 22 of these miRNA loci showed directionally concordant copy number variation.
For primary human monocytes, 19 of these 20 genes were directionally concordant with the microarray results in THP-1 cells and these same 19 were individually confirmed as significantly CO-suppressed (p<0.05, ANOVA post hoc contrast of LPS+CO vs. LPS; Table 1).
The qRT-PCR and microarray fold change ratios (Strain + Rejection Effect/Strain Effect) for these 4 genes were all directionally concordant.
This shows that for 35 of the 38 (i.e. 92%) these contigs, the RT-PCR data were directionally concordant with the microarray data.
This shows that for 35 of these 45 (i.e. 78%) contigs, the RT-PCR data were directionally concordant with the microarray data.
Similar(47)
There are 88 gene products whose mRNA and protein fold changes were both significant and directionally consistent with each other (i.e. concordant) and these have an overall positive correlation.
I think that was directionally the right thing to do".
A flag is a potent symbol, purporting to be the standard of a concordant nation.
"It does not appear to be a home run, but it is directionally positive".
Dirk Meyer, A.M.D.'s president and chief executive, called the performance "directionally correct," but not entirely satisfactory.
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CEO of Professional Science Editing for Scientists @ prosciediting.com