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In our configuration, the crystals are oriented in the axial direction readout on both sides by individual photodetector channels allowing the spatial resolution and the detection efficiency to be independent of each other.
ASL images were acquired with a 3D pCASL sequence that uses a pseudocontinuous labeling technique 15 and an FSE acquisition with an interleaved stack of spiral (outward direction) readout and a centric ordering in the slice-encoding direction, as shown in Figure 1.
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Log-transformed percent expression was subtracted between parents and hybrids to establish the direction and magnitude of change, where positive values for log(P1) − log(P2) indicate that P1 > P2, and the value itself gives a direct readout of the magnitude fold change; this is the same as taking the log-transformed ratio, log(P1/ P1/.
At the same time, the navigator echoes following the excitation pulse were used for correcting not only the misalignment between alternating echoes along readout direction but also the intersegment amplitude discontinuities along phase-encoding direction [ 5].
To minimize acquisition time and warming of the samples and the employed coil system, readout direction was placed in alignment with the longest dimension of the scanned objects.
Although the echo-shifting effect along the readout direction may also be quantified with the KESA method, it does not result in partial-Fourier DTI artifacts and thus is not quantified in this paper.
Care must be taken when increasing the spatial resolution in the readout direction, since this will necessitate a decrease in sampling time (increase in sampling bandwidth) for each point and a consequent loss of SNR.
The second DTI set had identical parameter settings as used for the first DTI set except that it was acquired with a reversed k-space readout direction enabling the removal of susceptibility artifacts during post-processing (Andersson et al. 2003).
The parameters of the sequence used were: TR=3.3 ms, echo time (TE =1.4 ms, flip angle =8°, k space matrix 100 phase encoding steps × 128 points in the readout direction, inversion time (TI =655 ms, and time between successive inversion pulses (TR0)=3000 ms.
The resistive chain technique resulting in two signals at each (X,Y) direction will perform the readout of the PSPMT's anode signals; the system is based on PCI electronics.
34, 35, 47, 48 The full spectrum of psychophysiological testing has not yet been exploited, possibly dynamic visual tests are a step in this direction, suitable for quantitative, longitudinal readouts.
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