In order to evaluate the potential therapeutic benefit of AE ablation and to decide if further research in this direction is warranted, in vivo proof-of-principle experiments are required.
Further investigation in this direction is warranted as it may provide a practical solution to realize low-cost fabrication of polymeric devices [2, 3, 4, 5, 6].
Future research in this direction is warranted.
Via the identification, measurement and valuation of the additional components provided as part of ACCHS care, the IHSD Template could indicate the amount of resources required to provide health services equitably, and further research in this direction is warranted.
While there are no known catalytic domains in Ecd to make it conventionally druggable, the increasing ability of researchers to design inhibitors that work by non-conventional mechanisms suggest that further studies in this direction are warranted.
Allowing the exposures to remain continuous is currently infeasible with this modified C&RT algorithm, due to computational challenges posed by the quantity of GLM models needed, and this direction warrants future methodological development.
Of these 1,503 SNPs, 173 had been tested also in Mayo tier 2. Eight of these SNPs had also p<0.05 in the Mayo tier 2 dataset and five of them (rs1000291 [chromosome 3], rs2241743 and rs2313982 [chromosome 4], rs3018626 [chromosome 11] and rs2282048 [chadmosome13]) had the same direction of effect and they would warrant further consideration based on this strategy (Table 2).
Further studies are warranted in the direction of utilizing these SNPs as biomarkers for prediction of treatment responsiveness to MSC therapy.
The review ends by considering directions that warrant further investigation in the future.
LH points in the direction of cost effectiveness, however further research is warranted with a broader costs perspective including long term effects as societal benefit, quality of life and survival.
