Sentence examples for direction of pathway from inspiring English sources

Modeling was guided by several principles in determining potential pathways of influence of one variable on another or, stated simply, the presence and direction of pathway arrows between variables in the path analysis model diagram.

Some students recognized that many of the processes depicted could be reversible, but others struggled to recognize that relative concentrations of molecules determine the direction of pathway flux at any given moment.

Second, the direction of pathway-level expression change is discordant between the two cohort datasets.

The diverse regulatory strategies and the different directions of pathway optimization in the context of various S. cerevisiae hosts are hypothesized to cause the host-specific responses to xylose utilizations.

Under positive selection, i.e. in the same direction as the pathway effect, all segregating loci in the pathway will show frequency shift in the direction of the pathway effect and following the order of S loci ≥T loci ≥B loci (particularly under additivity or in a RI/DH population).

His mathematical representation of life space also accounted for directions of pathways toward a goal and amount of attraction or repulsion toward a given object in the space.

Social, cultural, and health services factors are important in shaping both the direction and the duration of the care pathway 1. Ethnicity has the potential to influence the nature and direction of the pathway to care.

Next, all the member genes are sorted by their t-statistic values in accordance with the overall regulatory direction of the pathway; the most strongly up-regulated genes are arranged to the top for an overall up-regulated pathway, whereas the most strongly down-regulated genes are arranged to the top for an overall down-regulated pathway.

"There's tissue engineering and all sorts of application areas where we would want to switch a molecular process or change the fate and direction of the pathway," she said.

Under negative selection, i.e. in the opposite direction of the pathway effect, only null mutant alleles or repressors at upstream regulatory loci are responsive to selection and significant amounts of allelic diversity will remain at downstream loci.

However, a major limitation of the quantitative genetics approach was noted, i.e. the direction of a pathway (FGU) effect can not be determined if it is not involved in any epistasis, as seen in most of FGUs in the GA repressed pathways.