Aligned fibers of extracellular matrix (ECM) affect the direction, efficiency, and persistence of migrating cells.
The aim of the audit was to quantify the number of markers migrating, distance and direction of migration and conditions under which markers migrate.
The fraction of migrating cells correlated with the direction and magnitude of the gradient of oxygen (Fig. S4D-E).
In addition, neutrophils isolated from the Cdc42GAP knockout mice had an increased ability to migrate, but the direction of migration was disrupted [ 41].
Our time-lapse analysis of fz-2 MO-injected transgenic embryos shows that the insulin-positive cells still migrate, but their direction of migration is random indicating these cells have lost key positional information in the absence of the wnt5/fz2 signal (Fig. 1).
Nuclei of migrating cells incorporated bromodeoxyuridine.
7) The authors describe that 50% of posterior filopodia do not contain actin (in the subsection headed "Migrating PGCs extend specialized filopodia in the direction of migration").
Whereas motogens affect the ability of interneurons to migrate, chemorepellants and chemoattractants serve to provide migratory cells with the information about which direction to migrate.
As growth cones migrate, they extend dynamic lamellipodial and filopodial protrusions in the direction of migration.
Recently metamorphosed juveniles exiting the grassland side of the pond changed their direction of movement and migrated into the forested habitat.
