Sentence examples for directed to target from inspiring English sources

Moreover, synthetic siRNAs directed to target sites (core, NS3, NS4A and NS4B coding regions) in the HCV genome efficiently suppressed viral replication in a dose-dependent manner.

The design of chemical libraries directed to target classes is an activity that requires the availability of ligand pharmacological data and/or protein structural data.

From the beginning, care managers were directed to target asthmatics, diabetics, and high-volume utilizers of health care, using an array of markers to identify patients who needed management.

RISC is directed to target mRNAs by the mature miRNA guide strand [ 16].

Mature miRNAs are bound by the DICER complex and then directed to target mRNAs via a 6-bp seed sequence in their 5′ region (Lewis et al. 2005).

Previously, it has been demonstrated that human codon-optimized Cas9 nucleases can be directed to target sites in the human genome to induce precise cleavage at genomic loci in human cells (Cong et al, 2013; Mali et al, 2013).

Therefore, the design of new therapies directed to targets different from those classic dopaminergic ones is particularly relevant nowadays.

These might be a subpopulation with single terminations directed to targets different from that of neighboring neurons in the same projection focus.

Therefore, much attention is now directed to immunotherapy targeting tau protein [ 9- 12].

In some cases, the planes are directed to specific targets by Awacs radar planes or spotters on the ground.

Many novel therapeutic molecules are based on antibodies directed to molecular targets, including infectious pathogens.