Sentence examples for directed to modifications from inspiring English sources

In particular, our efforts will be directed to modifications of 10 devoted to obtain new derivatives active against HIV-1 mutant strains.

There were already 32 Silverplate B-29s in service with the Strategic Air Command, so the Air Material Command was directed to carry out Saddletree modifications on a further 80 B-29s, 36 B-50As, 23 B-50Bs and 18 B-36Bs.

Both mabs are directed to an O-linked carbohydrate modification (6-sulfo LacNAc) on PSGL-1 that is selectively expressed on a major population of myeloid derived human blood dendritic cells (DC).

Frequently C/D box sRNAs utilize both the D and D' guides to direct modification to separate targets within a region of 100 nucleotides in the rRNA sequence; these are called "double guide" sRNAs.

In this or a similar context, stimulation of PARP-1 sumoylation by association with intact DNA would help to direct the modification to chromatin-associated molecules.

Also, the approach used here could be interesting as alternative or addition to the directed modifications of enzymes to alter their catalytic characteristics.

Spermatozoal RNAs seem to possess the capacity to direct histone modifications and DNA methylation, for instance in response to paternal smoking [ 97], while the chromatin structure and DNA modifications in turn may affect transcription of RNAs.

In Tte sR152 the D box guide is responsible for directing modification to 23S U2880; the D' guide in this sRNA exhibits no significant complementarity to either 16S or 23S rRNA.

A third sRNA, Mka sR88 has a D guide that is similar to the D' guides in sR39 and 119 and may be capable of directing modification to position 16S G16S.

In parallel, much attention is paid to research and development of techniques for directed modifications of CNTs to prevent cytotoxicity.

The design and synthetic efforts were directed towards novel modifications to explore the protease binding region close to the S4 subsite.