Sentence examples for directed screening from inspiring English sources

Having established a proof-of-principle that eIF2B can be pharmacologically modulated, now enables directed screening efforts to identify new series of compounds and thereby enhance the probability of developing clinically useful pharmaceuticals that address currently unmet needs.

Through directed screening of compounds prepared as metalloprotease inhibitors a compound, CGS 30084, that had potent endothelin converting enzyme-1 (ECE-1) in vitro inhibitory activity (IC50=77 nM) was identified.

These findings imply that directed screening for iron overload and/or HFE mutations is unwarranted in type 2 diabetes.

Such studies are essential before directed screening for iron overload can be recommended in diabetic patients (12).

This, in turn, gives anti-doping laboratories a possibility to identify them even in directed screening procedures.

This combined information can be very valuable for a directed screening of microsatellite markers linked to CCR in populations segregating for microfibril angle in an attempt to validate this QTL in different populations or Eucalyptus species.

To pursue the idea that small RNA might play a role in dosage compensation, we conducted a directed screen of RNAi pathways.

In fact, directed screens against FDA-approved compounds have been successful in defining new activity for many commonly used and clinically relevant compounds [ 42].

Those are the people we should be directing screening resources toward.

For a time after his return, he worked for 20th Century Fox, directing screen tests (including one for Marilyn Monroe).

With his marriage crumbling, Minnelli spent a year directing screen tests before taking on the challenging assignment of adapting Gustave Flaubert's novel Madame Bovary.