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With the exception of the relatively few that are encoded by the mitochondrial and plastid genomes, proteins are synthetized in cytosolic ribosomes and are directed post-translationally to their final destination by means of an intricate system of sorting routes.
"It's a great idea and a fine project," said Salvatore F. Cordo, who directs Post's M.B.A. program.
After flirting with directing post-university, he veered into sound design, regularly working with Headlong and the Donmar Warehouse on Enron, Red, for which he won a Tony in 2010, and King Lear, for which he won an Olivier last year.
MicroRNA (miRNA) directs post-transcriptional regulation of a network of genes by targeting mRNA.
MicroRNAs (miRNAs) are small noncoding RNA molecules that act as sequence specificity guides to direct post-transcriptional gene silencing.
Through analysis of UNC93B1 mutants we identified an additional role for UNC93B1 in directing post-Golgi trafficking of TLR9.
Processed microRNAs guide the Argonaute protein (AGO2) of the RNA-induced silencing complex (RISC) to direct post-transcriptional repression of target mRNAs.
Thank you for sending your work entitled "A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing" for consideration at eLife.
Hence, Mafb provides a new example of a transcription factor that can direct post-synaptic differentiation, apparently in a cell-type specific manner.
The main function of miRNAs is to direct post-transcriptional regulation of gene expression, typically by binding to 3′UTR (untranslated region) of cognate mRNAs and inhibiting their translation and/or stability.
Another, more direct post read: "THE WORST DAY OF MY ENTIRE EXISTENCE.
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CEO of Professional Science Editing for Scientists @ prosciediting.com