Sentence examples for directed mismatch from inspiring English sources

This may be a further parallel between the more highly studied methyl directed mismatch repair pathway of E. coli and nick-directed mismatch repair.

Among the various cellular proofreading elements including the genes responsible for base selection, exonucleolytic editing, MMR (Methyl-directed Mismatch Repair), and DNA repair [ 15- 18], we chose the dnaQ gene which encodes the ϵ subunit of E. coli DNA polymerase III.

A related proposal on nick-instructed resolution has been made before (Gilbertson and Stahl 1996), and a recent model (Stahl and Foss 2010) posits that the position of a nick directs the mismatch repair machinery to heteroduplex regions at meiotic DSB.

In this paper, we formulate a common representation for six major interoperability conflicts that arise through discrepancies or direct mismatches among architectural properties of interacting components.

MeCP2 mutants were subsequently generated by site directed mutagenesis using mismatch primers according to manufacturer's protocol (Stratagene).

Mismatches are created, and the methyl-directed mismatch repair (MMR) system acts to eliminate the mismatches inhibiting recombination.

Key to these high frequencies is avoiding the methyl-directed mismatch repair system, which normally removes greater than 99% of the incorporated changes.

In Escherichia coli, errors in newly-replicated DNA, such as the incorporation of a nucleotide with a mis-paired base or an accidental insertion or deletion of nucleotides, are corrected by a methyl-directed mismatch repair (MMR) pathway.

Members of the Epsilonproteobacteria lack multiple genes in the methyl-directed mismatch repair system (MMR).

Both of these proteins are involved in nick-directed mismatch repair pathways.

This suggests that, if Class I methanogens have methyl-directed mismatch repair, they use a different system.