Sentence examples for directed dosing from inspiring English sources

Thus, given the effectiveness of warfarin nomograms in the general outpatient population, we evaluated whether an electronic warfarin anticoagulation nomogram administered by nurses was able to achieve similar effectiveness of anticoagulation compared to physician directed dosing, among outpatient hemodialysis patients.

When a patient winds up taking more than the directed dose, liver damage or even death can result.

This study included direct dosing of the neonates, and was designed specifically to investigate renal development and to ensure that the bioactive peptides were not associated with the same type of fetopathy exhibited by ACE inhibiting drugs.

Since an optimal study design for testing potential developmental neurotoxicants in rats, should include exposure during both the pre- and postnatal periods of brain development, we suggest that in the case of triclosan, direct dosing of pups may be the best way to obtain that goal.

In short, there is disagreement about whether direct dosing of pups precludes the need to control for litter effects (e.g., Eriksson 2008; Hardy and Stedeford 2008).

Further considerations of methodologic issues related to the conduct of the DNT study include an ILSI workshop on the direct dosing of preweaning mammals.

Table 11 shows the results of using a finer breakdown of time periods, made possible by the focus on data resulting from direct dosing at discrete times.

This workshop culminated in a monograph on direct dosing that has broad application to study design for many areas of research, for example, pharmaceuticals, environmental pollutants, and academic research (Moser et al. 2005; Zoetis and Walls 2003).

Although some investigators have set forth the argument that direct dosing of pups precludes the need to control for litter effects, a U.S. EPA cosponsored expert panel (Moser et al. 2005) evaluated this issue and concluded otherwise.

The draft TG 426 was distributed for comment in 1998, and significant technical issues identified by this review (e.g., the optimal duration of treatment, direct dosing of preweaning rodents, and conduct of morphometric evaluations) were further discussed at an expert consultation meeting in 2000 (OECD 2003).

A protocol directed ESA dose adjustment according to approved labeling [ 11], based on the most current Hb value measured 1 week previous to the planned administration.