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Much of his work – including National Lampoon's Animal House (1978), Meatballs (1979) and Ghostbusters (1984), all of which he co-wrote, and Caddyshack (1980), which he co-wrote and directed – changed the course of US film comedy, even if the prudish might argue that it was not for the better.
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This finding indicates that epigenetic changes accumulating with age are generally nondirectional or are the outcome of many smaller directed changes with, in part, opposite direction.
In contrast, directed change occurs when one group establishes dominance over another through military conquest or political control; thus, imperialism is the most common precursor to directed change.
Like incorporation, directed change involves the selection and modification of cultural characteristics.
"New breeding techniques like gene editing enable scientists to make precise, directed changes to the existing crop's genome.
Agrarian reform is a complex process of directed change, and its effects touch society in many ways.
James B. Cunningham, the deputy American representative, said that once imposed, sanctions should be kept in place until the leader against whom they are directed changes behavior.
Two major types of acculturation, incorporation and directed change, may be distinguished on the basis of the conditions under which cultural contact and change take place.
The processes that operate under conditions of directed change include forced assimilation the complete replacement of one culture by another and resistance against aspects of the dominant culture.
All the included editing tools are precise, allowing for very specific, directed changes to the images.
Discordantly directed changes in soluble and platelet PECAM-1 after the first 24 hours after thrombolytic therapy may represent redistribution of the whole PECAM-1 pool.
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