Direct Validation of Certificates (DVCert) [30] allows a client to validate the authenticity of a server certificate without having to rely on third parties at all.
Direct validation of editing was performed on a subset of the detected A-to-G sites using Sanger sequencing and deep sequencing.
These results provide direct validation of BLI imaging as a powerful and quantitative tool for the assessment of antineoplastic therapies in living animals.
In this study, we observed that MMP-2 and MMP-9 secretion was increased with estrogen treatment of ER+ thyroid cancer cells, which was suppressed by treatment with DIM, providing not only a correlative link but a direct validation of the anti-estrogenic activity of DIM that alters thyroid cancer cell phenotype.
The EST alignments were filtered based on requirements for minimum alignment length and sequence identity in order to differentiate cases in which the amino acid sequences were supported by a strong alignment from the cases in which the alignment indicated a paralog rather than a direct validation of the sequence by genomic data.
Moreover, the calculation of the gross margin in the production model allows a direct validation of the model with benchmarking data and therefore provides a solid foundation for disease impact studies.
Still, it "was a direct validation of Ralph's concept," says Kalinski, and vaccines designed more recently, he believes, are working better.
A direct validation of calculated versus directly measured values of free testosterone in premenopausal women was published by Vermeulen et al. (1999).
Although not a direct validation of our modeling approach, the results suggest that the model may indeed represent glucose/lactate physiology during the FSIGT.
Indeed, several sources of variation like degree of differential expression, spot intensity, array averaging and filtering, probe design, binding sites and variances in amplification methodologies prevent a direct validation of microarray results by qPCR.
