Sentence examples for direct trials of from inspiring English sources

Although the model parameters appear to favor bypass surgery, there have not been direct trials of the two types of surgeries.

An indirect estimate of the relative treatment effect A versus B can be formed by comparing direct trials of A versus C with trials of B versus C. A simple approach to combining the indirect and direct estimates of A versus B would be to take a weighted average, for example using an inverse variance weighting.

(C ) Examples of direct trials (left), inference of order 1 trials (middle) and inference of order 2 trials (right).

We investigated the impact of the number of direct comparison trials on various statistical properties of an indirect comparison while allowing the sample size of each direct trial to follow a uniform distribution from 20 to 500.

Comparative assessment of the different fluid modalities is hampered by a paucity of direct trials.

Conversely, increased fruit and vegetable (F&V) intake may reduce cardiovascular disease risk, although direct trial evidence of a mechanism by which this occurs in subjects with T2D is lacking.

Further evidence of the influence of dense grass competition on germination of woody native species can be seen in direct seeding trials of various indigenous woody species on steep hill country grassland, which indicates the need to control intense competition from existing vegetation, particularly exotic grasses (Davis et al. [2009]).

Moreover, the field of drug discovery and disease prevention largely depends on the tissue culture-based model system, majorly relying on high-throughput proteomics techniques, because there is no scope for direct human trials of newly developed lead molecules [ 83, 84].

However, currently there is no direct trial evidence examining the effect of rosuvastatin on clinical endpoints of CHD, whereas atorvastatin has been widely tested in this regard.

It is also important that researchers obtain material from sequential samples (with parallel outcome data), taken before and during treatment with conventional therapies, and from biologically directed innovative trials of targeted therapies.

There is also direct trial evidence for the efficacy of ACE inhibitors in preventing the decrease in LVEF observed in patients after high-dose chemotherapy (Cardinale et al, 2006).