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Developmental retardation or acceleration, or otherwise occurring deviations from standard development during embryonic and postembryonic life will activate genes that direct the developmental processes towards normality.
The homeotic gene Ultrabithorax (Ubx), located in the bithorax complex of Drosophila, encodes a family of closely related proteins that direct the developmental fates of posterior thoracic and anterior abdominal metameres.
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Researchers have pinpointed a genetic "master switch" that directs the developmental fate of embryonic stem cells from mice.
"This is an exciting and important study," says Harvard Medical School psychiatric researcher Martin Teicher, who directs the developmental biopsychiatry research program at McLean Hospital in Belmont, Massachusetts.
Sxl activity is sufficient to direct the entire developmental programs of both somatic and germline sex determination (Christiansen et al. 2002; Robinett et al. 2010; Salz 2011; Whitworth et al. 2012).
Managers should talk with direct reports before the developmental experience to understand their goals and to convey expectations.
So there is no direct information about the developmental type of the earliest eumetazoans.
It only took one or two factors to be under direct control of the developmental GRN to regulate the timing, directionality, onset, and termination of the heart cell precursors' journey.
Our analysis indicates that this is a relatively short list; we find only 24 genes appear to be both be overexpressed and be direct targets at the developmental stage we examined.
Although the gametophyte generation in vascular plants is small and has limited physiological capabilities, its cells must convey genes capable of directing the sporophytic developmental pattern, because the pattern is transmitted through the gametes to the zygote.
Interestingly, although activated astrocytes (the direct developmental progeny of the radial glia) remain within their lineage in vivo, they are able to give rise to self-renewing neurospheres and generate new astrocytes, neurons, and oligodendrocytes under more permissive in vitro conditions [ 38].
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