Sentence examples for direct requirement for from inspiring English sources

"That a direct requirement for most Americans to purchase any product or services seems an intrusive exercise of legislative power," Judge Silberman wrote, "surely explains why Congress has not used this authority before — but that seems to us a political judgment rather than a recognition of constitutional limitations".

Satellite cells formed in Pax7-null mice are rapidly depleted from muscle following birth [15] [17], but it is unknown whether this occurs as a result of defects acquired during development, or through a direct requirement for Pax7 postnatally.

It is possible that it is a consequence of the loss of expression of regulatory genes during hindbrain segmentation, or there might be a direct requirement for Med12 function in proliferation or in the synthesis of components of the machinery that supports DNA replication and cell division.

Alternatively, the relationship between ept and Dome localization could indicate a direct requirement for ept in Dome endolysosomal trafficking in much the same way that ESCRT mutants block the vesicular movement and lysosomal turnover of the Notch receptor [4] [6], [47].

One possibility is that bps1 signal synthesis has a direct requirement for GSH.

Our results identify a direct requirement for ezrin in Src-induced VEGF-C expression in breast carcinoma cells.

Mouse cell culture studies support a pioneer factor role for Pbx proteins in mouse skeletal muscle differentiation (Berkes et al., 2004; de la Serna et al., 2005), but direct requirements for Pbx proteins in mammalian skeletal muscle have not yet been tested.

Analyses of several intron-containing MIRs in SR protein mutants allowed us to ascertain our conclusion concerning the direct requirement of introns for proper miRNA biogenesis.

However, it is currently unclear whether the failure of Sst and Pva induction indicates a direct requirement of Lhx6 for the differentiation and maturation of cortical interneurons or instead reflects the delayed migration and abnormal distribution of these cells in the pallium.

Third, Cdk9, being a subunit of P-TEFb, is known to phosphorylate RNAPII CTD, Spt5 C-terminal domains, and NELF, which together form protein complexes, suggesting a possible direct requirement of RNAPII or NELF phosphorylation for the manisfestation of NSpt5's effect.

Domestic direct requirement matrices for the 2009 national input output tables of China, Japan, and the U.S. were used for inter-regional comparison.