Sentence examples for direct rationale from inspiring English sources

A thorough understanding of disease pathophysiology is necessary to direct rationale design of therapeutic strategies.

These findings provide a direct rationale to developing novel, efficient, and well-tolerated targeted therapies for IBC patients.

Our finding that the suppression of SYN inhibits IL-1β-induced synovial fibroblast proliferation provides a direct rationale for SYN as a potential target for the treatment of RA.

When the kids laud Sanders for being "logical" or "clever," they are speaking of the logic of his activism his cause-and-direct-effect rationale for stepping in, his eagerness to revamp the entire system more than his adeptness as a political strategist.

When the kids laud Sanders for being "logical" or "clever," they are speaking of the logic of his activism — his cause-and-direct-effect rationale for stepping in, his eagerness to revamp the entire system — more than his adeptness as a political strategist.

Subsequently, several modifications were made to the model in order to improve its fit by deleting parameters that were not significant and by distinguishing (on the basis of theoretical rationales) direct and indirect effects.

When announcing the proposals, Scottish Football Association Stewart Regan responded to a question about fans' desire for a bigger top flight by saying he hoped to work with Supporters Direct to explain the rationale for the 12-12-18 plan.

Skutsch adds that "while it is clear that the communities themselves need to be part of the overall plan" for battling climate change, she "cannot quite see the rationale for direct payments" to indigenous groups for forest conservation.

In nursing research, Benner et al. [ 4] define intuition as 'a judgment without a rationale, a direct apprehension and response without recourse to calculative rationality'.

The high incidence of OA after injury highlights a potential opportunity to improve population health and is a strong rationale to direct increased efforts toward primary prevention of knee injury and improved management of knee injury.

These results further support the rationale for direct or indirect targeting of PCs, which provide additional benefit to patients, provided that any such approach is not associated with an unacceptable safety profile.