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Settlement negotiations were said to have begun in earnest in mid-May, with a direct presentation to the plaintiffs' lawyers by G. Allen Andreas, the chief executive of Archer Daniels, who is a cousin of Michael Andreas.
Many of these were patients whose pathway to diagnosis bypassed primary care, for example, through direct presentation to an emergency department.
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Recently, Xu and coworkers reported that direct antigen presentation to CD8+ T cells is sufficient to prime an efficient anti-viral cytotoxic response [40], which would enable these cells to fully activate upon VACV infection in the absence of T cell helper.
As migratory dendritic cells, LCs are capable of direct antigen presentation to cytotoxic T cells.
Monocytes have previously been shown to be required for activation of Vγ9Vδ2 T cells by the N-BP pamidronate (Miyagawa et al, 2001), although the role of monocytes was thought to be direct presentation of N-BP to the Vγ9Vδ2 TCR (Miyagawa et al, 2001).
If plasmid DNA is taken up and the antigen directly expressed and processed in, and/or secreted by, DCs, then that would lead to direct presentation of the encoded antigen(s) to CD8+ and/or CD4+ T cells, respectively.
To assess how exposure to social distress subsequently influences freezing behavior, it was first necessary to evaluate the freezing responses of BALB and B6 mice to direct presentation of the CS (see Fig. 1f) and the paired CS-UCS (see Fig. 1c).
Whatever the mechanism, cross-presentation of viral antigens was at least as efficient as direct presentation by PDC exposed to influenza virus.
It is unclear why direct presentation of tumor-antigens to autologous T cells by NSCLC cells should result in the expansion of antigen non-specific DP T lymphocytes.
Synthetic HCV peptides have been used to induce T-cell immunity through direct presentation on antigen-presenting cells (Table 1).
Reversely, the possibility that MHCII-peptide complexes are transferred from donor-derived stromal cells to circulating dendritic cells is indeed a possibility, and may occur in addition to the direct presentation of antigen by stromal cells, as we have shown in Figure 4.
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