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As there is no experimental evidence for the direct positive feedback that has been posited in current models of trichome initiation, the question of whether the system can support bistability without it is one of great interest.
Hence, beetles most likely develop a preference when gaining a direct positive feedback in terms of an improved performance, whereby the current experience matters the most.
Previous network models of the central pluripotency genes regularly assumed a direct positive feedback regulation from Nanog acting on Oct4 and Sox2.
This is not unexpected, as direct positive feedback and non-linearity are often prerequisites for bistability in simple systems [ 15, 20].
Recently, a mathematical model for the decision between the Epi and the PrE fate has been proposed (Bessonnard et al., 2014), in which Nanog and Gata6 repress each other, and reinforce their own expression through direct positive feedback.
However, although recent work has suggested that a positive feedback loop may be involved in cell fate specification in the root epidermis [ 28], no such direct positive feedback has been found in the leaf.
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Finally, possible relationships for both seagrass density – total nitrogen and seagrass density – sediment grain size could even be bidirectional, causing direct positive feedbacks.
Children are taught through instruction, directed positive feedback, observation, and role-play.
Here, we demonstrate that PLD isozymes, PLD1 and PLD2 are direct targets and positive feedback regulators of the Wnt/β-catenin signaling.
Here we propose a model for the regulation of SMC phenotype by a complex network of indirect and direct positive and negative feedback loops by SM miRNAs, SRF, and additional transcriptional factors.
With a dropoff in positive feedback, direct from the market, corporate sustainability commitments will be much harder to justify in the short term, especially if – as many have predicted – the global economy slows down.
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