Sentence examples for direct lymphocytes from inspiring English sources

An important function of this molecule is to direct lymphocytes to E-cadherin-expressing epithelial cells [21].

Under pathological conditions, such as RA, chemokines direct lymphocytes into the chronically inflamed synovial tissue [ 7, 8].

Current understanding of antigen presentation and the maturation of dendritic cells has opened the way for a more rational design of new adjuvants, intended not only to deliver the antigen to antigen presenting cells (APC) and to induce APC maturation, but also to direct lymphocyte differentiation towards either Th1 or Th2 phenotypes, and to deal with disease-induced immunodepression.

Reaction initiation and severity may be explained by the release of chemokines from macrophages under oxidative stress and/or direct lymphocyte cytotoxicity [ 47- 50].

Direct infection of lymphocytes might induce unchecked proliferation of a normal or a susceptible (preleukemic) lymphocyte to produce ALL; either persistent infection or malignant transformation triggered by past infection (one cleared from the body some time before ALL is diagnosed) is a conceivable route from direct lymphocyte infection to ALL.

Altogether, the studies have shed light on factors involved in directing lymphocytes into inflamed tissue and maintaining inflammation in Sjögren's syndrome.

One of the prominent roles of chemokines is directing lymphocyte migration from the bloodstream to lymphoid organs or to sites of inflammation (Nibbs & Graham, 2013).

Originally, chemokines ('chemotactic cytokines') and their receptors gained substantial scientific interest because of their central role in orchestrating immune responses by directing lymphocyte movement to the thymus, lymphoid tissues, and sites of inflammation (Luster, 1998).

Lymphocytes are notoriously hard to transduce with RNAi payloads and are disseminated throughout the body, often located in deep tissues; therefore, developing an efficient systemic delivery system directed to lymphocytes is not a trivial task.

Dendritic cells (DC) play a major role in the innate immune response by directing B lymphocytes and T lymphocytes.

While the current immunosuppressive therapies are mainly directed against lymphocyte activation and proliferation, other cellular populations have largely been overlooked so far.