They may direct interact with signaling kinases (PKCs, JNKs and IKKs) in cells [ 7].
If ct v) is an empty set, it denotes that node v does not direct interact with any co-target that we set in the experiment.
This further suggests that the vertebrate TACCs have gained the specific ability to direct interact with transcriptional regulatory complexes, and that bridging protein(s) are no longer required.
I appreciate that the authors did a lot of work, and the calculations are technically sound, but the net result achieved will be very misleading for any reader who really wants to know which proteins in M.tuberculosis physically or direct interact with the human host.
Specifically, myosin, a direct interacting partner with F-actin, is a motor protein.
Western blot analysis of these preparations demonstrated the co-purification of Ozz and its direct interacting partner Elo C with the thin-thick filaments, indicating an association of the entire Ozz-E3 complex with fully assembled myosin (Fig. 5A).
The imaginary fourth wall between the audience and the acting characters enabled a more direct interacting between the characters with more natural vocal delivery and smaller gestures, in stead of large stylized acting.
However, under these stringent experimental conditions (high salt concentration), while we were able to demonstrate Ozz binding with its direct interacting partners, MyHCemb and Elo C, we could not co-immunoprecipitate the remaining components of the Ozz-E3 complex (not shown).
CBP does not establish direct interactions with DNA, but interacts with a large diversity of DNA-binding transcription factors.
In addition to its direct interaction with MLL2, ER may interact with the HMT complex via other proteins, such as Menin and activating signal cointegrator-2 (ASC-2).
