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They may direct interact with signaling kinases (PKCs, JNKs and IKKs) in cells [ 7].
If ct v) is an empty set, it denotes that node v does not direct interact with any co-target that we set in the experiment.
This further suggests that the vertebrate TACCs have gained the specific ability to direct interact with transcriptional regulatory complexes, and that bridging protein(s) are no longer required.
I appreciate that the authors did a lot of work, and the calculations are technically sound, but the net result achieved will be very misleading for any reader who really wants to know which proteins in M.tuberculosis physically or direct interact with the human host.
Similar(55)
Zeb-1 has 19 direct interacting DEmiRNAs, based on predicted interactions.
The final interaction network of interest contained the disease proteins (nodes) and their direct interacting partners (edges).
Here, we analyze the performance of using direct interacting neighbors and second level interacting neighbors.
Whether frataxin and ISD11 have direct interacting surfaces still needs to be determined.
Specifically, myosin, a direct interacting partner with F-actin, is a motor protein.
The second level interacting neighbors were used when we were unable to use direct interacting neighbors, in order to improve coverage.
By contrast, the cross-talk pathway is mediated by RIG-I·MAVS direct interacting with the IKKα-NF-κB inducing kinase (NIK) complex, in an IKKγ -independent manner [13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com